San Diego Padres vs Pittsburgh Pirates Prediction 05/04/2025 | MLB

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This Sunday will conclude this interesting series between the San Diego Padres and the Pittsburgh Pirates, two teams with very different records, but who often offer entertaining games.

San Diego Padres vs Pittsburgh Pirates: Padres Moneyline

The Padres are in the middle of a road trip, where they won in their first stop, in Pittsburgh, but they won’t have it easy here, as they will face Andrew Heaney (ERA 2.50), who is one of the home team’s best starters. However, the Padres will also have a reliable pitcher on the mound, Nick Pivetta, who is coming off a 7.0-inning outing with no runs and only 2 hits allowed against the Detroit Tigers, bringing his ERA down to 1.78. With both teams having good pitchers, the better offense will make the difference, so I expect the Padres to be the ones to win.

Injuries for San Diego Padres:

F. Tatis Jr. Day to day.

M. McCoy Out.

J. Cronenworth Out.

J. Merrill Out

Injuries for Pittsburgh Pirates:

E. Rodríguez Out.

N. Gonzales Out.

J. Oviedo Out.

J. Lawrence Out.

San Diego Padres vs Pittsburgh Pirates: Under 8.5

The Pirates’ offense is one of the worst in the league, averaging just 3.42 runs scored per game, so they will have a lot of trouble against a Pivetta who is coming in a great moment. However, the possible absence of Tatis Jr. significantly affects the Padres’ offense, who will have a lot of work to decipher a Heaney who has done a great job this season.

San Diego Padres vs Pittsburgh Pirates Prediction

Although on paper the Padres are far superior, on this occasion they will not have things easy as they have to face a Heaney who has allowed one run or less in four of his six starts. However, their offense is much better than the home team, which will suffer a lot to damage an inspired Pivetta.

The odds provided are an estimate, please check before you bet.