Pittsburgh Pirates vs St. Louis Cardinals Prediction 05/05/2025 | MLB

MoneyLine Pick ✔✔✔✔✔

Cardinals

--101

Total Under Points ✔✔✔✔✔

Under

--101

Table of Content

Two old rivals from the National League Central Division will be facing off this Monday when the Pittsburgh Pirates visit Busch Stadium to take on the St. Louis Cardinals, in a clash of teams in need of wins.

Pittsburgh Pirates vs St. Louis Cardinals: Reds

Although they have been more competitive than expected, the Pirates haven’t been able to put together many good results, even being up to 10 games below .500. Their main problem is the offense, given that they average just 3.35 runs scored per game. Also, their pitching isn’t solid either, and today they’ll have Carmen Mlodzinski on the mound, who has had quite a few problems, posting an ERA of 6.95. That’s music to the ears of the Cardinals, who also have a negative record, but at least have been more productive on offense, averaging 4.55 runs scored per game. The Cardinals have a 10-6 record at home, and considering that they will have Mike Mikolas as their starter, who has allowed only two runs in his last two starts, we expect them to take another win.

Injuries for Pittsburgh Pirates:

I. Kiner-Falefa Out.

J. Lawrence Out.

E. Rodriguez Out.

Injuries for St. Louis Cardinals:

Z. Thompson Out.

I. Herrera Out.

Pittsburgh Pirates vs St. Louis Cardinals: Under

The Pirates’ offensive problems are considerable, especially away from home, so they will have many problems here against a Mikolas who limited the Braves to 6.0 innings without runs in his previous start. However, although the Cardinals are usually somewhat productive, they aren’t a team that scores many runs, so we expect this to be a game with few total runs.